Factors Limiting SOS Expression in Log-Phase Cells of Escherichia coli

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Factors limiting SOS expression in log-phase cells of Escherichia coli.

In Escherichia coli, RecA-single-stranded DNA (RecA-ssDNA) filaments catalyze DNA repair, recombination, and induction of the SOS response. It has been shown that, while many (15 to 25%) log-phase cells have RecA filaments, few (about 1%) are induced for SOS. It is hypothesized that RecA's ability to induce SOS expression in log-phase cells is repressed because of the potentially detrimental ef...

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5 6 7 8 9 10 Shawn C. Massoni, Michael C. Leeson, Jarukit Edward Long, Kristin Gemme, Alice Mui 11 and Steven J. Sandler * 12 13 14 15 16 17 18 Department of Microbiology 19 Morrill Science Center IV N203 20 University of Massachusetts at Amherst 21 Amherst, MA 01003 22 23 24 25 Running title: Mechanistic requirements of SOS in radA mutants 26 27 28 29

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2012

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.00674-12